Glucose metabolism in renal tubular function
نویسندگان
چکیده
منابع مشابه
Renal tubular function in hyperparathyroidism.
Renal tubular function was assessed in a group of patients with mild hyperparathyroidism before and after a mean period of 2.7 years conservative management. It was also assessed, before and after a mean of 3.3 years following surgery in a group of patients with initially higher plasma calcium concentration. Mean maximum urine osmolality was within the accepted range as was the maximum urine pl...
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A partial differential Progressive Tubular Reabsorption (PTR) model, describing renal tubular glucose reabsorption and urinary glucose excretion following a glucose load perturbation, is proposed and fitted to experimental data from five subjects. For each subject the Glomerular Filtration Rate was estimated and both blood and urine glucose were sampled following an Intra-Venous glucose bolus. ...
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OBJECTIVE We determined prevalence, risk factors, phenotype, and pathophysiological mechanism of new-onset diabetes after transplantation (NODAT) to generate strategies for optimal pharmacological management of hyperglycemia in NODAT patients. RESEARCH DESIGN AND METHODS Retrospective cohort study comparing demographics, laboratory data, and oral glucose tolerance test (OGTT)-derived metaboli...
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It is known that glucose is filtered through the glomerulus in the same concentration as it is present in the water of the plasma (Walker and Reisinger, 1933), and that, its absence from the urine at normal plasma concentrations is due to the circumstance that it is reabsorbed by the tubule. In the amphibian kidney, this reabsorption is effected by the proximal segment (Walker and Hudson, 1937)...
متن کاملSGK1-sensitive renal tubular glucose reabsorption in diabetes.
The hyperglycemia of diabetes mellitus increases the filtered glucose load beyond the maximal tubular transport rate and thus leads to glucosuria. Sustained hyperglycemia, however, may gradually increase the maximal renal tubular transport rate and thereby blunt the increase of urinary glucose excretion. The mechanisms accounting for the increase of renal tubular glucose transport have remained...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1986
ISSN: 0085-2538
DOI: 10.1038/ki.1986.8